PreSENTIA: Colorectal

Synonyms: -

Material:

Buccal swab

TAT:

2-3 weeks

Method:

NGS

Overview

Colorectal cancer is a genetic disease in which the cells in the colon or rectum divide uncontrollably forming tumors. In 2020, colorectal cancer was the 3rd most common type of cancer worldwide. Hereditary colorectal cancer accounts for about 5-10% of all colorectal cancer cases ¹. Patients with an inherited germline mutation have increased risk of developing colorectal cancer in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

PreSENTIA Colorectal cancer panel tests for numerous germline mutations in 17 genes that could cause colorectal cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

PreSENTIA: Colorectal

17 Gene(s)*

APC

BMPR1A

CDH1

CHEK2

EPCAM

GREM1

MLH1

MSH2

MSH6

MUTYH

PMS2

POLD1

POLE

PTEN

SMAD4

STK11

TP53

Who is the test for

How many hereditary cancer syndromes are associated with this panel

Recommendations by professional bodies

References

Created by

Our editorial team consists of medical specialists and scientists in the field of human genetics. All content is created and reviewed in accordance with current scientific standards.

Last Update : 01.10.2026

How to order a genetic test

Select the right test for your patients. Contact our team in case you do not have an active contract yet.

Collect the sample. Download and fill in the order and consent form or access our portal (available for sample sent to Germany).

Properly pack the sample and send it to Medicover Genetics.

The sample will be analysed in our accredited laboratories.

An actionable report will be available for you to access safely and securely.

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