PreSENTIA: Colorectal High-Risk

Synonyms: -

Material:

Buccal swab

TAT:

2-3 weeks

Method:

NGS

Overview

Colorectal cancer is a genetic disease in which the cells in the colon or rectum divide uncontrollably forming tumors. In 2020, colorectal cancer was the 3rd most common type of cancer worldwide. Hereditary colorectal cancer accounts for about 5-10% of all colorectal cancer cases¹. Patients with an inherited germline mutation have increased risk of developing colorectal cancer in the future. The genes tested in this panel have been identified to increase the risk of developing cancer in the future.

PreSENTIA Colorectal High-Risk cancer panel tests for numerous germline mutations in 10 genes that could cause colorectal cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.

PreSENTIA: Colorectal High-Risk

10 Gene(s)*

APC

BMPR1A

EPCAM

MLH1

MSH2

MSH6

MUTYH

PMS2

SMAD4

STK11

Who is the test for

How many hereditary cancer syndromes are associated with this panel

Recommendations by professional bodies

References

Created by

Our editorial team consists of medical specialists and scientists in the field of human genetics. All content is created and reviewed in accordance with current scientific standards.

Last Update : 01.10.2026

How to order a genetic test

Select the right test for your patients. Contact our team in case you do not have an active contract yet.

Collect the sample. Download and fill in the order and consent form or access our portal (available for sample sent to Germany).

Properly pack the sample and send it to Medicover Genetics.

The sample will be analysed in our accredited laboratories.

An actionable report will be available for you to access safely and securely.

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