OVERVIEW

WHAT IS ADVENTIA

Adventia is a new genetic test for carrier screening to determine whether a phenotypically healthy person is a carrier of a genetic disease. The genetic insight provided by Adventia can inform, guide and empower people on their reproductive choices and minimize the risk of people who are carriers transmitting a genetic disease to their children. Adventia offers a choice of different panels and testing for up to 229 moderate to severe autosomal recessive and X-linked genetic diseases.

WHY GET TESTED?

Anyone can carry certain mutations (genetic changes) in their body. Some mutations may have no effect on our health and development, while others can cause a genetic disease. When an individual has a mutation in one of their genes, that individual is a carrier of a recessive disease. Two carriers of the same recessive disease can have a child who is affected, if the child inherits the mutation from both of them.

As carriers are asymptomatic, they are unaware of their carrier status and the risk of passing a mutation to their children. In fact, many mutations for recessive diseases could be inherited via multiple generations without clinical manifestation. Unless you have been tested, it is impossible to know whether you are a carrier of a recessive disease.

WHO COULD BENEFIT FROM ADVENTIA

Adventia is a beneficial and comprehensive test for everyone based on a novel and powerful technology and can provide meaningful results in a short turn-around time to help you minimize your risk of transmitting a genetic disorder to your children.

top-banner

Couples planning to start their
families and want to know
about their carrier status

top-banner

High-risk population groups
for specific diseases

top-banner

People with a family history of a
genetic mutation

WHAT DOES ADVENTIA TEST FOR?

Adventia screens for autosomal recessive and X-linked diseases.
Carriers of recessive diseases have one healthy gene and one gene with the mutation.

Autosomal Recessive

Autosomal Recessive Diseases affect chromosome pairs 1 to 22. If both parents are carriers, they have:
– 1 in 4 chance of having an unaffected child
– 1 in 2 chance of having a child who is also a carrier, who has inherited the mutation from only one parent
– 1 in 4 chance of having an affected child, who has inherited mutations from both parents.

X-Linked

X-Linked Diseases affect the X chromosome, found on the 23rd chromosome pair which determines gender.
– 1 in 2 chance of having a carrier daughter. Female carriers may or may not exhibit disease characteristics due to X-inactivation*
– 1 in 2 chance of having an affected son. Males who have inherited the mutation are always affected, as they only have one X chromosome.

ADVENTIA PANELS

Adventia tests for autosomal recessive and X-linked diseases which have moderate to
severe phenotype, are high in carrier frequency, can compromise quality of life and
may be manageable through early interventions.

bodymap
FOCUS PANELS
GUIDELINES-BASED PANEL
COMPREHENSIVE PANEL
HOW CAN I TAKE THE ADVENTIA CARRIER SCREENING?
circle-icon

Ask your healthcare provider about Adventia

circle-icon

Your healthcare provider will collect a cheek swab sample from you

circle-icon

The sample will be sent to our laboratory

circle-icon

The sample will be analyzed in our laboratory

circle-icon

Results will be sent to your healthcare provider within 2-3 weeks

ACCEPTED MATERIAL

Cheek swab using ADVENTIA kit

TURNAROUND TIME

10-15 working days

OUR NETWORK