Atrial fibrillation (AF) affects around 33 million people worldwide and is the most common cardiac arrhythmia. Its prevalence is about 0.4% in the general population but increases to approximately 6% in individuals over 65 years of age. AF results from uncoordinated electrical activity in the atria, leading to a rapid and irregular heartbeat, which raises the risk of sudden cardiac death. Risk factors include age, obesity, hypertension, and diabetes. The prognosis depends on the clinical profile and genetic predispositions. Familial atrial fibrillation is increasingly diagnosed; recent studies have found a positive family history in 15% of AF patients.
SCIENTIFIC BACKGROUND
GJA5, GJC1, KCNA5, KCNH2, KCNQ1, LMNA, MYL4, NPPA, SCN5A, TBX5, TTN
GENES
GJA5, GJC1, KCNA5, KCNH2, KCNQ1, LMNA, MYL4, NPPA, SCN5A, TBX5, TTN
ASSOCIATED TESTS
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