SCIENTIFIC BACKGROUND

ATM, BRCA1, BRCA2, CHEK2, EPCAM*, HOXB13, MLH1, MSH2, MSH6, PALB2, PMS2

Prostate cancer is a common disease that affects 1 in 7 men from middle age. The severity of the disease varies greatly between individuals, where in some cases, a tumor may slowly grow during a person’s lifetime with no negative health impact, while in others, tumors can aggressively metastasize and become life-threatening. A few mutations have been linked to hereditary prostate cancer, and variants in specific genes, such as BRCA2 or HOXB13, correlate with life-threating forms of prostate cancer.

 

 

*CNV analysis only

Genes in bold are recommended by International guidelines, including German expert panels and/or have been more often associated with specific cancers.

GENES
ATM, BRCA1, BRCA2, CHEK2, EPCAM*, HOXB13, MLH1, MSH2, MSH6, PALB2, PMS2
How to order